According to the new International Society for Sexual Medicine (ISSM) guidelines, PE is defined as “ejaculation that always occurs after less than 1 minute of vaginal penetration from the first sexual experience (lifelong PE), or a clinically significant and bothersome reduction in latency time, often ≤3 minutes (acquired PE),and the inability to delay ejaculation on all or nearly all vaginal penetrations, and negative personal consequences, such as distress, frustration and/or the avoidance of sexual intimacy.” Paroxetine is one of the SSRIs, which increase the amount of 5-hydroxytryptamine (5-HT) in postsynaptic membrane receptors and thus delay ejaculation.
According to the new International Society for Sexual Medicine (ISSM) guidelines, PE is defined as “ejaculation that always occurs after less than 1 minute of vaginal penetration from the first sexual experience (lifelong PE), or a clinically significant and bothersome reduction in latency time, often ≤3 minutes (acquired PE),and the inability to delay ejaculation on all or nearly all vaginal penetrations, and negative personal consequences, such as distress, frustration and/or the avoidance of sexual intimacy.” Paroxetine is one of the SSRIs, which increase the amount of 5-hydroxytryptamine (5-HT) in postsynaptic membrane receptors and thus delay ejaculation.
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